Bacteriophage, or bacterial viruses, can and have been exploited for decades for the application termed “phage display”. This strategy involves the engineered expression of a peptide(s) of interest fused to the minor and/or major coat protein of a tolerant phage. New and surprising applications of phage display are emerging, including the display of a diverse set of peptides, to clinical applications including vaccine delivery.
We have generated a novel system of phage display that is tune-able, which can prove very important in design, based on the therapeutic application. By using different suppressor strains of E. coli in combination with our patented inducible fusion production platform we can modulate surface expression of our peptide/protein of interest.
Find out more about the researcher: Jessica