Shirley Wong, B.Sc.

Ph.D. Candidate
School of Pharmacy
University of Waterloo

shirley.wong@uwaterloo.ca

Education:

  • Bachelor of Science, Honours Biomedical Science, University of Waterloo, Waterloo ON 

About:

Shirley is currently enrolled in the Doctoral program at the School of Pharmacy, working under the supervision of Dr. Roderick Slavcev. Previously, Shirley completed an undergraduate degree in Biomedical Sciences at the University of Waterloo. Her research interests lie in the area of gene therapy and she is currently working on developing an ovarian cancer gene therapy strategy using DNA Ministrings created by the Slavcev Lab as well as a novel 1-step production/purification system for the production of intelligent Phage Assembled Gene Expression Strings (iPhAGES).

AWARDS:

  • NSERC CGS-D Scholarship (2016-2019)
  • UW President's Scholarship (2014-2019)
  • NSERC CGS-M Scholarship (2014-2015)
  • UW Provost's Entrance Award for Excellence (2013)
  • UW Provost's Master Entrance Award for Women (2013)

PUBLICATIONS:

  • Wong. S., Lam, P., Nafissi, N., Denniss, S. & Slavcev, R.A. (2016). Production of double-stranded DNA ministrings. J Vis Expts 108: e53177, doi: 10.3791/53177

  • Wong S. & Slavcev, R.A. (2015). DNA Ministrings: Linear covalently closed  minivectors for use in non-viral  gene therapy with applications toward ovarian cancer. Mol Therapy 23: P75. 

  • Wong, S. & Slavcev, R. A. (2015). Treating cancer with infection: A review on bacterial cancer therapy. Lett Appl Microbiol. 61: 107-112. doi: 10.1111/lam.12436

BOOK Contributions:

  • Nicastro, J., Wong, S., Khazaei, Z., Lam, P., Blay, J., Slavcev, R. A. Bacteriophage Applications — Historical Perspective and Future Potential. Springer Nature Publishing; 2016. doi:10.1007/978-3-319-45791-8
    • Nicastro, J., Wong, S., and Slavcev, R. A. Bacteriophages functionalized for gene delivery and the targeting of gene networks. In: Bacteriophage Applications — Historical Perspectives and Future Applications, Springer Nature Publishing; 2016. 29-38.

    • Wong, S. Phage probiotics. In: Bacteriophage Applications — Historical Perspectives and Future Applications, Springer Nature Publishing; 2016. 39-58.

    • Nicastro, J., Wong, S., and Slavcev, R. A. Phage-mediated immunomodulation. In: Bacteriophage Applications — Historical Perspectives and Future Applications, Springer Nature Publishing; 2016. 69-82.

RECENT PRESENTATIONS:

Invited Lectures

  • Wong, S., and Nicastro, J. “Pharmaceutical Dosage Forms - Biotechnology Products” (2017). Presented for PHARM 125 - Pharmaceutics; University of Waterloo, School of Pharmacy; Waterloo, ON.

Oral Presentations

  • Wong, S., Slavcev, R. A. (2017). "Optimizations in the production of DNA ministrings, linear-covalently closed DNA minivectors for use in non-viral gene therapy" American Society of Gene & Cell Therapy 20th Annual Meeting: Washington, DC, USA. Molecular Therapy 25:5S1 S358. doi: 10.1016/j.ymthe.2017.04.025.

Poster Presentations

  • Wong, S., Nafissi, N., Slavcev, R. A. (2016). "Engineering a system for the production of linear covalently-closed DNA minivectors" Nano Ontario 7th Annual Conference; Guelph, ON, Canada.

  • Wong, S., Slavcev, R. A. (2016). "DNA Ministrings: a new approach to cancer gene therapy." Institute for Comparative Cancer Investigation 8th Annual Cancer Research Symposium; Guelph, ON, Canada.

  • Wong, S., Slavcev R. A. (2015). "DNA Ministrings: linear-covalently closed minivectors for use in non-viral gene therapy with applications toward ovarian cancer." American Society of Gene & Cell Therapy 18th Annual Meeting; New Orleans, LA, USA.

  • Wong, S., Nafissi, N., Sum, C. H., Slavcev, R. A. (2014). "Delivery of toxic topoisomerase mutant alleles by DNA ministrings for ovarian cancer gene therapy." Institute for Comparative Cancer Investigation 7th Annual Cancer Research Symposium; Guelph, ON, Canada.