A Featured Platform
Our Patented DNA ministrings are the safest and most efficacious DNA vectors for nonviral gene delivery. Their topology as linear covalently closed (stable) “strings” makes them the safest tools for therapeutic DNA delivery or genomic manipulation to date.
We designed the production platform this way from inception, and we have tested and published these outcomes in Nature affiliate journals. DNA ministrings are made through a simple shift in temperature in bacteria which makes them scalable and inexpensive to produce versus competitors that fall dramatically short in terms of production efficiency. Our current application targets colorectal (CRC) as proof of principle. Future targets include prostate cancer, intractable disease and monogenic disorders such as cystic fibrosis